Blood replacement with nanobiotechnologically engineered hemoglobin and hemoglobin nanocapsules

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Blood replacement with nanobiotechnologically engineered hemoglobin and hemoglobin nanocapsules.

Unlike donor red blood cells (RBCs), blood substitutes can be treated to remove infective agents and can be used on the spot or in the ambulance in emergency without the time-consuming typing and cross-matching. Donor RBC requires storage at 4 degrees and is only good for 42 days, but blood substitutes can be stored for much longer time. For example, a bovine polyhemoglobin (PolyHb) can be stor...

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comparing mean hemoglobin levels of umbilical cord blood in neonates with maternal hemoglobin and delivery pattern

introduction hemoglobin (hb) levels in fetus increase with progression of pregnancy, reaching highest levels in life. hb serves as iron reserve in fetus and is needed for the infant to adapt with anemia. many factors can decrease hb levels at birth and lead to accelerated physiological anemia. hence, the infant would require earlier administration of iron drops. identification of these factors ...

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Heterozygote Hemoglobin J Iran in Combination with Hemoglobin H Disease

This is a report concerning a concurrent case of hemoglobin J Iran (Hb J Iran) and Hemoglobin H (Hb H) disease in an Iranian woman. The patient was coincidentally found during the course of routine pre-marital genetic counselling for her son. The diagnosis of heterozygote Hb J Iran for her son, ultimately led to the diagnosis of concurrent Hb J Iran and Hb H disease. The hematological examinati...

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Cord Hemoglobin in Newborns in Correlation with Maternal Hemoglobin in Northeastern Iran

Background: Hemoglobin (Hb) and hematocrit (Hct) have been used routinely in the diagnosis of neonatal anemia and polycythemia. Objective: To measure the cord blood Hb and Hct and to determine their association with maternal Hb and Hct. Methods: 170 healthy neonates born through normal vaginal delivery with gestation age of 37-42 wks and birth weight of 2.5-4 kg, and their mothers were included...

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Hemoglobin Function in Stored Blood

INTRODUCTION The ultimate aim in transfusing blood is the maintenance or restoration of a medium for the transport of oxygen to body tissues. Most often, the efficacy of transfusion therapy is evaluated by survival of the donor erythrocytes in the recipient. However, red cells may have a normal in vivo survival yet be unable to bind and unload oxygen physiologically. In 1956, Valtis and Kennedy...

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ژورنال

عنوان ژورنال: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology

سال: 2010

ISSN: 1939-5116

DOI: 10.1002/wnan.95